Aussie students re-create Martin Shkreli's $750 HIV pill for about $20

But now, he may have been bested by a few Australian high school students.

And they did it for AU$20 (about $15, 12).

One of the students on the team, Brandon Lee, described the feeling of making the final discovery.

“At first there was definitely disbelief,” Lee told the ABC.

So what’s it like to beat Big Pharma at their own game?

To use an Aussie phrase, student Milan Leonard was pretty stoked.

“It was ecstatic, it was bliss, it was euphoric,” he said.

His tweets were more direct.

“Learning synthesis isn’t innovation,” hewrote in one tweet.

“And never, ever compare your cook game to mine.

Highest yield, best purity, most scale.

I have the synthesis game on lock,” helater added.

CNET contacted Sydney Grammar for comment, but the students were at their end of year Speech Day.

First published December 1, 2:24 p.m. AEDT.